Preheat oven to 375°F. Spray a large 13 x 18-inch sheet pan with nonstick baking spray.
Pile nuts in the middle of the prepared pan and pour on honey, orange juice, sugar, salt, Cajun seasoning, cayenne, and thyme leaves. Mix together and spread out to an even layer on the baking pan.
3 cups unsalted mixed nuts, ½ cup honey, ¼ cup fresh orange juice, 2 tablespoons light brown sugar, 2 teaspoons kosher salt, 1 ½ tablespoons Cajun seasoning (I use Morton & Bassett), ½ teaspoon cayenne pepper, 1 tablespoon fresh thyme leaves
Bake in preheated oven 18-25 minutes, stirring every eight minutes until the liquid condenses and becomes thick, coating the nuts like a glaze.
Remove from oven and cool, continuing to stir and breaking up any large pieces. Serve at room temperature. These can be made 1 day in advance and stored in an airtight container.